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A New medical imaging technique for diagnosing dermatologic diseases: a clue to treatment choices

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posted on 2022-01-05, 10:23 authored by Massimo Fioranelli, Alireza Sepehri, Maria Grazia Roccia, Aracena Jahaira Carolina, Iva Binic, Masa Golubovic, Michael Tirant, Nguyen Van Thuong, Julia Sigova, Torello Lotti, Aroonkumar Beesham
Recently, it has been shown that DNA could emit some waves which carry main information about its evolution. Using this idea, we design a new method to image the behavior of skin cells, especially melanocytes, and diagnose their damage. In this method, we make use of a circuit which is formed from DNAs within the damaged melanocytes, a graphene sheet, DNAs within the healthy cells, and a scope. To amplify exchanged waves between hexagonal and pentagonal manifolds of DNAs, we induce some defects in the graphene sheets and replace some hexagonal mole?cules by pentagonal ones to build a structure similar to the structure of DNAs. We show that unprotected exposure to UVA and UVB damages the DNA in melanocyte cells, producing genetic defects, or mutations, that can lead to exchanged waves between cells and the emergence of a current in our circuit. By analyzing the evolu?tion of this current, we can estimate the rate of destruction in melanocytes, and pre?dict the emergence of cancer.

Funding

National Research Foundation, Grant/Award Number: 118511; Guglielmo Marconi University

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